Cady Heron is a hit with The Plastics, the A-list girl clique at her new school, until she makes the mistake of falling for Aaron Samuels, the ex-boyfriend of alpha Plastic Regina George.
Lindsay Lohan
as Cady Heron
Rachel McAdams
as Regina George
Lizzy Caplan
as Janis Ian
Lacey Chabert
as Gretchen Wieners
Amanda Seyfried
as Karen Smith
Daniel Franzese
as Damian
Jonathan Bennett
as Aaron Samuels
Rajiv Surendra
as Kevin Gnapoor
Tina Fey
as Ms. Norbury
Tim Meadows
as Mr. Duvall
Ana Gasteyer
as Cady's Mom
Neil Flynn
as Cady's Dad
