When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.
Jeff Goldblum
as Professor Brody
Elizabeth Perkins
as Mrs. Brody
Alexander Pollock
as Scotty Brody
Miriam Margolyes
as Sophie the Castle Maid
Tobey Maguire
as Lou the Beagle (voice)
Alec Baldwin
as Butch (voice)
Sean Hayes
as Mr. Tinkles (voice)
Susan Sarandon
as Ivy (voice)
Joe Pantoliano
as Peek (voice)
Michael Clarke Duncan
as Sam (voice)
Jon Lovitz
as Calico (voice)
Charlton Heston
as The Mastiff (voice)
