Stuart, an adorable white mouse, still lives happily with his adoptive family, the Littles, on the east side of Manhattan's Central Park. More crazy mouse adventures are in store as Stuart, his human brother, George, and their mischievous cat, Snowbell, set out to rescue a friend.
Michael J. Fox
as Stuart Little (voice)
Melanie Griffith
as Margalo (voice)
Nathan Lane
as Snowbell (voice)
Geena Davis
as Mrs. Little
Hugh Laurie
as Mr. Little
Jonathan Lipnicki
as George Little
Steve Zahn
as Monty (voice)
James Woods
as Falcon (voice)
Maria Bamford
as Teacher
Anna Hoelck
as Martha Little
Ashley Hoelck
as Martha Little
Kevin Olson
as Irwin
