After solving their last mystery at Spooky Island, the Mystery Inc. gang is back in Coolsville, where they are being honored with their very own exhibit at the Coolsonian Criminology Museum. However, when a masked villain steals costumes of classic monsters on display and brings them to life, the gang must come out of retirement to solve the case.
Freddie Prinze Jr.
as Fred
Sarah Michelle Gellar
as Daphne
Matthew Lillard
as Shaggy
Linda Cardellini
as Velma
Neil Fanning
as Scooby-Doo Voice / Tasmanian Devil (voice)
Seth Green
as Patrick
Peter Boyle
as Old Man Wickles
Tim Blake Nelson
as Jacobo
Alicia Silverstone
as Heather
Pat O'Brien
as Pat O'Brien
Bill Meilen
as Chauffeur
Zahf Paroo
as Ned
