Ace assassin Frank Kitchen is double crossed by gangsters and falls into the hands of rogue surgeon known as The Doctor who turns him into a woman. The hitman, now a hitwoman, sets out for revenge, aided by a nurse named Johnnie who also has secrets.
Michelle Rodriguez
as Frank Kitchen / Tomboy
Sigourney Weaver
as Dr. Rachel Kay
Tony Shalhoub
as Dr. Ralph Galen
Caitlin Gerard
as Johnnie
Anthony LaPaglia
as Honest John Hartunian
Paul McGillion
as Paul Wincott
Ken Kirzinger
as Nurse Albert Becker
Paul Lazenby
as Bodyguard
Zak Santiago
as Edward Gonzales
Adrian Hough
as Sebastian
Alex Zahara
as Vladimir Gorski
Chad Riley
as Merchado
