Archeologist and avid puzzle solver Professor Layton and his assistant Luke are caught up in an adventure when a masked figure steals an entire opera house and forces those in attendance to play a high-stakes game. The winner will receive eternal life, but it could mean death for the losers.
大泉洋
as Professor Layton (voice)
堀北真希
as Luke Triton (voice)
相武紗季
as Emmy Altava (voice)
水樹奈々
as Janice Quatlane (voice)
渡部篤郎
as Jean Descole (voice)
大塚芳忠
as Inspector Clamp Grosky (voice)
家弓家正
as Oswald Whistler (voice)
折笠富美子
as Melina Whistler (voice)
井上喜久子
as Celia Raidley (voice)
諸星すみれ
as Nina (voice)
飯塚昭三
as Curtis O'Donnell (voice)
三宅健太
as Marco Brock (voice)
