The three brothers discover that the human experiment banned after destroying the "Orochi", is still going on to secretly revive the evil snake. They also find out that some ex-members of the Yamainu (the Japanese military unit formed to kill the snake) are behind this conspiracy. The brothers fight together again in a battle against the military.
梶裕貴
as Soramaru Kumo (voice)
中村悠一
as Tenka Kumo (voice)
代永翼
as Chutaro Kumo (voice)
能登麻美子
as Nishiki (voice)
鳥海浩輔
as Sosei Abeno (voice)
安元洋貴
as Seiichiro Takamine (voice)
下野紘
as Rakucho Takeda (voice)
大原さやか
as Kiiko Sasaki (voice)
藤原祐規
as Mutsuki Ashiya (voice)
藤原貴弘
as Zenzo Inukai (voice)
岩崎ひろし
as Chenran Shi (voice)
