This musical is based on four short stories by Damon Runyon. In one tale, gambler Feet Samuels sells his body to science just as he realizes that Hortense loves him and that he would rather live than die. In another story, Harriet's parrot is killed, and she has problems dealing with her loss. Then, there is a gambler, "Regret", who has bloodhounds on his trail when he becomes a murder suspect. Finally, "The Brain" is bleeding profusely, and his friends search for a way to save his life through a blood transfusion.
Matt Dillon
as Regret
Jennifer Grey
as Lovey Lou
Julie Hagerty
as Harriet MacKyle
Rutger Hauer
as The Brain
Madonna
as Hortense Hathaway
Esai Morales
as Handsome Jack
Anita Morris
as Miss Missouri Martin
Randy Quaid
as Feet Samuels
Josef Sommer
as Waldo Winchester
Alan Ruck
as John Wangle
Dinah Manoff
as Maud Milligan
Ethan Phillips
as Basil Valentine
