Jonathan Drake, while attending his brother's funeral, is shocked to find the head of the deceased is missing. When his brother's skull shows up later in a locked cabinet, Drake realizes an ancient curse placed upon his grandfather by a tribe of South American Jivaro Indians is still in effect and that he himself is the probable next victim.
Henry Daniell
as Dr. Emil Zurich
Valerie French
as Alison Drake
Grant Richards
as Lt. Jeff Rowan
Paul Wexler
as Zutai
Eduard Franz
as Jonathan Drake
Frank Gerstle
as Det. Lee Coulter
Lumsden Hare
as Rogers, the butler
Howard Wendell
as Dr. George Bradford
Paul Cavanagh
as Kenneth Drake
Jonathan Hole
as Funeral Director (uncredited)
Arthur Tovey
as Minister at Funeral (uncredited)
Bert Stevens
as Mourner at Funeral (uncredited)